Experienced in mammalian cell expression platforms, Shengming Bio has obtained manufacture-authorized cell lines of CHOZN, DG44, HD-BIOP3, etc. The company owns independent-development vector systems, such as pRCA single expression frame vector, pRCB double expression frame vector, etc. Shengming Bio can provide high-quality and inclusive services according to clients’ unique needs by replying upon extensive experience in programs and sound equipment and facilities.  

Only with primary sequence of protein：

◆Nucleic acid sequence optimization, vector construction, transient evaluation;

◆Stable transfection, cell pool screening, monoclonal screening, stability qualification, and cell bank establishment;

◆Experienced in cell line development of monoclonal antibodies, bispecific antibodies, and fusion proteins;

◆Cell line development and manufacturing experience of CHOZN, HD-BIOP3, CHO-K1, CHO-S, DG44, DUXB11, HEK293, etc.; 

◆300m² GMP workshop, Grade C purification, and automatic cell filling system to ensure the homogeneity of cell bank;

◆Storage system for gas phase liquid nitrogen with 24h full-monitoring and remote alarming;

◆Traceable documentation that comply with regulation.